Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 14/20 | 0.44 |
| ▸ | GPR183 | P32249 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.39 |
| ▸ | ACACB | O00763 | 4/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL470547 | 0.86 | GPR119 (0.45) | GPR119GPR183HRH4ACACBKCNH2 | |
| SCHEMBL470522 | 0.80 | GPR119 (0.50) | GPR119GPR183KCNH2 | |
| SCHEMBL387798 | 0.74 | GPR119 (0.77) | GPR119GPR183KCNH2 | |
| SCHEMBL470651 | 0.74 | ALOX5AP (0.36) | GPR119GPR183ACACBKCNH2 | |
| SCHEMBL389269 | 0.74 | GPR119 (0.77) | GPR119GPR183KCNH2 | |
| SCHEMBL384502 | 0.74 | GPR119 (0.77) | GPR119GPR183KCNH2 | |
| SCHEMBL12064553 | 0.74 | GPR119 (0.38) | GPR119GPR183KCNH2 | |
| SCHEMBL470661 | 0.74 | GPR119 (0.47) | GPR119GPR183HRH4ACACBKCNH2 | |
| Hydrochloric Acid SCHEMBL461678 | 0.72 | DPP4 (0.46) | GPR119GPR183KCNH2 | |
| SCHEMBL12064798 | 0.71 | GPR119 (0.40) | GPR119GPR183KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |