Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 9/20 | 0.51 |
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | CASP3 | P42574 | 2/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.49 |
| ▸ | RELA | Q04206 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5291491 | 0.85 | MAPK1 (0.51) | L3MBTL1RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL28764679 | 0.84 | L3MBTL1 (0.66) | L3MBTL1RAB9ANPC1KMT2ASMN1; SMN2 | |
| SCHEMBL29837506 | 0.84 | L3MBTL1 (0.66) | L3MBTL1RAB9ANPC1KMT2ASMN1; SMN2 | |
| SCHEMBL5233290 | 0.84 | RAB9A (0.51) | RAB9ANPC1KMT2ASMN1; SMN2NFKB1 | |
| SCHEMBL3001084 | 0.82 | KMT2A (0.60) | L3MBTL1RAB9ANPC1KMT2ASMN1; SMN2 | |
| SCHEMBL29738593 | 0.82 | KMT2A (0.60) | L3MBTL1RAB9ANPC1KMT2ASMN1; SMN2 | |
| SCHEMBL29738591 | 0.82 | KMT2A (0.60) | L3MBTL1RAB9ANPC1KMT2ASMN1; SMN2 | |
| SCHEMBL5200379 | 0.81 | KMT2A (0.53) | KMT2AMEN1 | |
| SCHEMBL18070988 | 0.80 | L3MBTL1 (0.60) | L3MBTL1RAB9ANPC1KMT2ASMN1; SMN2 | |
| SCHEMBL13923493 | 0.78 | SMN1; SMN2 (0.61) | L3MBTL1RAB9ANPC1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1824844-B1 | PYRAZINE DICARBOXAMIDES AND THE USE THEREOF | BAYER HEALTHCARE AG (DE) | 2008-11-05 | — | — | EP | disclosed |
| EP-1819701-A1 | CYCLIC IMINOCARBAMATES AND USE THEREOF | Bayer HealthCare AG (DE) | 2007-08-22 | — | — | EP | disclosed |
| WO-2006058630-A1 | CYCLIC IMINOCARBAMATES AND USE THEREOF | BAYER HEALTHCARE AG (DE) | 2006-06-08 | — | — | WO | disclosed |