Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 9/20 | 0.47 |
| ▸ | TP53 | P04637 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4708765 | 0.84 | L3MBTL1 (0.51) | RAB9ANPC1TP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL4885704 | 0.82 | KMT2A (0.64) | RAB9AMAPTKDM4ENPC1TP53 | |
| SCHEMBL5200379 | 0.81 | KMT2A (0.53) | KMT2AHCRTR1 | |
| SCHEMBL5291491 | 0.74 | MAPK1 (0.51) | RAB9AMAPTKDM4ENPC1ALDH1A1 | |
| SCHEMBL16885484 | 0.73 | NPC1 (0.57) | RAB9AMAPTKDM4ENPC1TP53 | |
| SCHEMBL4283746 | 0.73 | NPC1 (0.57) | RAB9AMAPTKDM4ENPC1TP53 | |
| SCHEMBL2636192 | 0.73 | RAB9A (0.78) | RAB9AMAPTKDM4ENPC1TP53 | |
| SCHEMBL3529609 | 0.71 | KDM4E (0.72) | RAB9AMAPTKDM4ENPC1TP53 | |
| SCHEMBL30281726 | 0.71 | RAB9A (0.68) | RAB9AMAPTKDM4ENPC1TP53 | |
| SCHEMBL21709858 | 0.70 | KDM4E (0.82) | RAB9AMAPTKDM4ENPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1819701-A1 | CYCLIC IMINOCARBAMATES AND USE THEREOF | Bayer HealthCare AG (DE) | 2007-08-22 | — | — | EP | disclosed |
| WO-2006058630-A1 | CYCLIC IMINOCARBAMATES AND USE THEREOF | BAYER HEALTHCARE AG (DE) | 2006-06-08 | — | — | WO | disclosed |