Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7604181 | 0.83 | SMN1; SMN2 (0.55) | MEN1GAAKMT2ATACR1TEAD3 | |
| SCHEMBL7633589 | 0.83 | MEN1 (0.47) | MEN1GAAKMT2ATEAD3LTA4H | |
| SCHEMBL4708973 | 0.81 | TSHR (0.49) | MEN1GAAKMT2ATEAD3ALDH1A1 | |
| SCHEMBL7608951 | 0.80 | ALDH1A1 (0.56) | MEN1KMT2ATACR1ALDH1A1KDM4E | |
| SCHEMBL4758662 | 0.79 | ALDH1A1 (0.44) | MEN1GAAKMT2ATEAD3ALDH1A1 | |
| SCHEMBL7603640 | 0.79 | HRH1 (0.34) | TACR1ALDH1A1HRH1HRH2CYP2C19 | |
| SCHEMBL20305813 | 0.74 | MEN1 (0.62) | MEN1GAAKMT2ATACR1TEAD3 | |
| SCHEMBL20305526 | 0.73 | MEN1 (0.54) | MEN1GAAKMT2ATEAD3NPC1 | |
| SCHEMBL7612299 | 0.73 | TACR1 (0.35) | TACR1 | |
| SCHEMBL5405877 | 0.72 | LTA4H (0.51) | MEN1GAAKMT2ATEAD3LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927173-B1 | SUBSTITUTED [2-(1-PIPERAZINYL)ETHOXY]METHYL | UCB SA (BE) | 2002-06-12 | — | — | EP | claimed |