SCHEMBL4710205

SCHEMBL4710205

COC(=O)C[C@@H]1S[C@@H](c2cccc(OC)c2OC)c2cc(Cl)ccc2NC1=O.COC(=O)C[C@@H]1S[C@H](c2cccc(OC)c2OC)c2cc(Cl)ccc2NC1=O

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CDYL2 Q8N8U2 1/20 0.46
CDYL Q9Y232 1/20 0.46
HTT P42858 1/20 0.43
HSD17B10 Q99714 1/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
FDFT1 P37268 3/20 0.39
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4112411 1.00 CDYL2 (0.46) CDYL2CDYLHTTHSD17B10MEN1
SCHEMBL4112406 1.00 CDYL2 (0.46) CDYL2CDYLHTTHSD17B10MEN1
SCHEMBL4123403 1.00 CDYL2 (0.46) CDYL2CDYLHTTHSD17B10MEN1
SCHEMBL4112415 1.00 CDYL2 (0.46) CDYL2CDYLHTTHSD17B10MEN1
SCHEMBL4710208 1.00 CDYL2 (0.46) CDYL2CDYLHTTHSD17B10MEN1
SCHEMBL4123398 1.00 CDYL2 (0.46) CDYL2CDYLHTTHSD17B10MEN1
SCHEMBL4710206 1.00 CDYL2 (0.46) CDYL2CDYLHTTHSD17B10MEN1
SCHEMBL13776093 0.92 CDYL2 (0.44) CDYL2CDYLMEN1KMT2AFDFT1
SCHEMBL4116387 0.92 CDYL2 (0.44) CDYL2CDYLMEN1KMT2AFDFT1
SCHEMBL4123249 0.91 CDYL2 (0.46) CDYL2CDYLFDFT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1939205-A1 TRICYCLIC COMPOUND Daiichi Sankyo Company, Limited (JP) 2008-07-02 EP disclosed