Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.66 |
| ▸ | GLA | P06280 | 1/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA7 | P43166 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL852214 | 0.81 | POLB (0.57) | POLBGLAPKMHTTHPGD | |
| SCHEMBL30264508 | 0.81 | POLB (0.57) | POLBGLAPKMHTTHPGD | |
| SCHEMBL28457831 | 0.81 | CA1 (0.56) | POLBGLAPKMCA12CA1 | |
| SCHEMBL10167028 | 0.81 | PKM (0.67) | POLBGLAPKMHTTMAPT | |
| SCHEMBL5024162 | 0.79 | POLB (0.58) | POLBGLAPKMHTTHPGD | |
| SCHEMBL9464873 | 0.78 | POLB (0.57) | POLBGLAPKMHTTHPGD | |
| SCHEMBL288153 | 0.78 | NPC1 (0.62) | POLBGLAPKMHTTHPGD | |
| SCHEMBL2693394 | 0.77 | PKM (0.62) | POLBGLAPKMHTTMAPT | |
| SCHEMBL14058837 | 0.77 | CA1 (0.52) | POLBGLACA12CA1CA2 | |
| SCHEMBL2693176 | 0.76 | THRB (0.62) | POLBGLAPKMHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879877-A2 | ANTIMICROBIAL AGENTS | Ranbaxy Laboratories Limited (IN) | 2008-01-23 | — | — | EP | claimed |
| WO-2006117762-A2 | ANTIMICROBIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | claimed |