Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3647706 | 1.00 | NR1H2 (0.31) | NR1H2 | |
| SCHEMBL9040147 | 0.79 | ALDH1A1 (0.34) | — | |
| SCHEMBL5537141 | 0.76 | CHRNA4 (0.43) | NR1H2 | |
| SCHEMBL3397031 | 0.76 | CHRNA4 (0.43) | NR1H2 | |
| SCHEMBL9942309 | 0.76 | — | — | |
| SCHEMBL14324896 | 0.76 | — | — | |
| SCHEMBL23663758 | 0.76 | NR1H2 (0.51) | NR1H2 | |
| SCHEMBL1135376 | 0.76 | NR1H2 (0.51) | NR1H2 | |
| SCHEMBL22010186 | 0.76 | NR1H2 (0.51) | NR1H2 | |
| SCHEMBL4900183 | 0.76 | NR1H2 (0.51) | NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863817-B1 | SUBSTITUTED, BICYCLIC 8-PYRROLIDINO-BENZIMIDAZOLES, METHOD FOR THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS | SANOFI AVENTIS (FR) | 2008-05-28 | — | — | EP | disclosed |
| EP-1863817-A1 | SUBSTITUTED, BICYCLIC 8-PYRROLIDINO-BENZIMIDAZOLES, METHOD FOR THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS | sanofi-aventis (FR) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006099940-A1 | SUBSTITUTED, BICYCLIC 8-PYRROLIDINO-BENZIMIDAZOLES, METHOD FOR THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS | SANOFI-AVENTIS (DE) | 2006-09-28 | — | — | WO | disclosed |
| EP-0481274-B1 | 7-(2,7-Diazabicyclo[3.3.0]octyl)-3-quinolone- and -naphthyridonecarboxylic acid derivatives | BAYER AG (DE) | 1996-10-23 | — | — | EP | disclosed |
| EP-0393424-B1 | Process for the preparation of 2,7-Diazabicyclo(3.3.O)octanes | BAYER AG (DE) | 1995-09-27 | — | — | EP | disclosed |
| EP-0481274-A1 | 7-(2,7-Diazabicyclo[3.3.0]octyl)-3-quinolone- and -naphthyridonecarboxylic acid derivatives | BAYER AG (DE) | 1992-04-22 | — | — | EP | disclosed |
| EP-0393424-A2 | Process for the preparation of 2,7-Diazabicyclo(3.3.O)octanes | BAYER AG (DE) | 1990-10-24 | — | — | EP | disclosed |