Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3647706 | 0.79 | NR1H2 (0.31) | — | |
| SCHEMBL4711086 | 0.79 | NR1H2 (0.31) | — | |
| SCHEMBL2409560 | 0.77 | CHRM1 (0.42) | ALDH1A1TDP1JAK1POLB | |
| SCHEMBL9045042 | 0.75 | ALDH1A1 (0.33) | ALDH1A1SOAT1 | |
| SCHEMBL6212474 | 0.75 | ALDH1A1 (0.33) | ALDH1A1SOAT1 | |
| SCHEMBL9043872 | 0.73 | CHRM1 (0.35) | ALDH1A1SOAT1TDP1JAK1KMT2A | |
| SCHEMBL9042747 | 0.73 | ALDH1A1 (0.32) | ALDH1A1SOAT1 | |
| SCHEMBL9042008 | 0.71 | ALDH1A1 (0.32) | ALDH1A1SOAT1 | |
| SCHEMBL9044675 | 0.71 | ALDH1A1 (0.32) | ALDH1A1SOAT1 | |
| SCHEMBL9042786 | 0.68 | TP53 (0.33) | ALDH1A1SOAT1TDP1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481274-B1 | 7-(2,7-Diazabicyclo[3.3.0]octyl)-3-quinolone- and -naphthyridonecarboxylic acid derivatives | BAYER AG (DE) | 1996-10-23 | — | — | EP | disclosed |
| EP-0393424-B1 | Process for the preparation of 2,7-Diazabicyclo(3.3.O)octanes | BAYER AG (DE) | 1995-09-27 | — | — | EP | disclosed |
| EP-0481274-A1 | 7-(2,7-Diazabicyclo[3.3.0]octyl)-3-quinolone- and -naphthyridonecarboxylic acid derivatives | BAYER AG (DE) | 1992-04-22 | — | — | EP | disclosed |
| EP-0393424-A2 | Process for the preparation of 2,7-Diazabicyclo(3.3.O)octanes | BAYER AG (DE) | 1990-10-24 | — | — | EP | disclosed |