Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16713403 | 0.76 | L3MBTL1 (0.38) | MEN1KMT2AUSP2GAAL3MBTL1 | |
| SCHEMBL12549725 | 0.76 | L3MBTL1 (0.38) | MEN1KMT2AGAAL3MBTL1ALDH1A1 | |
| SCHEMBL10816228 | 0.76 | L3MBTL1 (0.41) | MEN1KMT2AGAAL3MBTL1ALDH1A1 | |
| SCHEMBL12549880 | 0.73 | HSD17B10 (0.46) | GAAL3MBTL1ALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL12549883 | 0.72 | MAPT (0.42) | MEN1KMT2AUSP2CASP1CASP7 | |
| SCHEMBL7651483 | 0.72 | GAA (0.37) | MEN1KMT2AUSP2GAAL3MBTL1 | |
| SCHEMBL513356 | 0.68 | L3MBTL1 (0.64) | GAAL3MBTL1ALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL25122976 | 0.65 | MEN1 (0.51) | MEN1KMT2AUSP2CASP1BRCA1 | |
| SCHEMBL4711987 | 0.65 | L3MBTL1 (0.35) | MEN1KMT2AGAAL3MBTL1ALDH1A1 | |
| SCHEMBL11319011 | 0.65 | TP53 (0.46) | GAAL3MBTL1TDP1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1996566-A1 | BEZOTHIAZOL DERIVATIVES AS BETA2 ADRENORECEPTOR AGONISTS | AstraZeneca AB (SE) | 2008-12-03 | — | — | EP | claimed |
| WO-2007106016-A1 | BEZOTHIAZOL DERIVATIVES AS BETA2 ADRENORECEPTOR AGONISTS | ASTRAZENECA AB (SE) | 2007-09-20 | — | — | WO | claimed |