SCHEMBL7651483

SCHEMBL7651483

CCn1c(=O)sc2cccc(S(=O)(=O)O)c21

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.37
TSHR P16473 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
L3MBTL1 Q9Y468 4/20 0.35
HTT P42858 2/20 0.35
POLB P06746 1/20 0.35
KDM4E B2RXH2 4/20 0.35
PKM P14618 1/20 0.35
ALDH1A1 P00352 4/20 0.35
RAB9A P51151 1/20 0.35
MAPT P10636 4/20 0.34
TP53 P04637 3/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
USP2 O75604 1/20 0.34
LMNA P02545 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
MYC P01106 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14699496 0.83 ALDH1A1 (0.42) GAATSHRNPSR1L3MBTL1HTT
SCHEMBL12549725 0.75 L3MBTL1 (0.38) GAATSHRNPSR1L3MBTL1HTT
SCHEMBL16713403 0.75 L3MBTL1 (0.38) GAATSHRNPSR1L3MBTL1HTT
SCHEMBL4613534 0.68 NPC1 (0.38) GAAKDM4EALDH1A1RAB9AMAPT
SCHEMBL4613536 0.68 NPC1 (0.38) GAAKDM4EALDH1A1RAB9AMAPT
SCHEMBL11319011 0.64 TP53 (0.46) GAANPSR1L3MBTL1HTTPOLB
SCHEMBL2523958 0.63 GABRA1 (0.46) POLBKDM4EMEN1KMT2AUSP2
SCHEMBL1269675 0.62 TTR (0.52) GAATSHRPOLBKDM4EALDH1A1
SCHEMBL3052609 0.62 MYC (0.39) MYC
SCHEMBL29945070 0.62 GPR3 (0.45) GAAPOLBALDH1A1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1014787-A4 ADJUVANT FOR TRANSCUTANEOUS IMMUNIZATION US GOV SEC ARMY (US) 2002-08-07 EP disclosed
EP-1014787-A1 ADJUVANT FOR TRANSCUTANEOUS IMMUNIZATION The Government of the United States of America, as represented by The Secretary of the Army (US) 2000-07-05 EP disclosed
WO-1998020734-A1 ADJUVANT FOR TRANSCUTANEOUS IMMUNIZATION THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1998-05-22 WO disclosed
US-5426037-A Filling dialysis tube with hybridomas; bubble; oscillation MEDICAL RESEARCH COUNCIL (GB) 1995-06-20 US disclosed
EP-0589915-A1 PRODUCTION OF MONOCLONAL ANTIBODIES MEDICAL RESEARCH COUNCIL (GB) 1994-04-06 EP disclosed
WO-1992022634-A1 PRODUCTION OF MONOCLONAL ANTIBODIES MEDICAL RESEARCH COUNCIL (GB) 1992-12-23 WO disclosed