Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR2E1 | Q9Y466 | 2/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 7/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PHGDH | O43175 | 2/20 | 0.33 |
| ▸ | GSR | P00390 | 1/20 | 0.33 |
| ▸ | XPO1 | O14980 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30242169 | 0.89 | NR2E1 (0.57) | NR2E1NR3C1NR3C2CYP1A2AR | |
| SCHEMBL27684812 | 0.84 | TDP1 (0.41) | NR3C1NR3C2CYP1A2GPR119GRM5 | |
| SCHEMBL31003556 | 0.83 | GPR119 (0.38) | NR2E1NR3C1NR3C2CYP1A2AR | |
| SCHEMBL7315540 | 0.73 | HPGD (0.38) | NR2E1NR3C1NR3C2 | |
| SCHEMBL7309063 | 0.71 | HPGD (0.39) | NR3C1NR3C2ARGPR52GPR119 | |
| SCHEMBL12247671 | 0.71 | GRM5 (0.49) | NR3C1NR3C2CYP1A2GRM5 | |
| SCHEMBL9288141 | 0.71 | TUBB4A (0.47) | NR3C1NR3C2GPR119GRM5PTGS1 | |
| SCHEMBL7316258 | 0.70 | HPGD (0.35) | NR3C1NR3C2 | |
| SCHEMBL7317980 | 0.70 | HPGD (0.35) | ARGRM5 | |
| SCHEMBL13122900 | 0.69 | NOTUM (0.37) | NR3C1NR3C2GPR52GPR119GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1922309-A1 | N-PHENYL-2-PYRIMIDINE-AMINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Il Yang Pharm. Co. Ltd. (KR) | 2008-05-21 | — | — | EP | disclosed |
| WO-2007018325-A1 | N-PHENYL-2-PYRIMIDINE-AMINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | IL-YANG PHARM. CO., LTD. (KR) | 2007-02-15 | — | — | WO | disclosed |