Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4712463 | 0.86 | GRM5 (0.49) | GRM5 | |
| SCHEMBL4713871 | 0.84 | GRM5 (0.42) | GRM5 | |
| SCHEMBL4711597 | 0.84 | GRM5 (0.44) | GRM5 | |
| SCHEMBL4711486 | 0.80 | GRM5 (0.46) | GRM5 | |
| SCHEMBL4711268 | 0.77 | GRM5 (0.43) | GRM5 | |
| SCHEMBL22366278 | 0.77 | HTT (0.54) | MAPT | |
| SCHEMBL4710798 | 0.77 | GRM5 (0.54) | GRM5 | |
| SCHEMBL22319687 | 0.76 | MAPT (0.52) | MAPT | |
| SCHEMBL19402109 | 0.76 | MAPT (0.52) | MAPT | |
| SCHEMBL4710432 | 0.70 | GRM5 (0.53) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0998459-B1 | PYRIDINE DERIVATIVES | NOVARTIS AG (CH) | 2008-04-23 | — | — | EP | claimed |
| EP-0998459-A2 | PYRIDINE DERIVATIVES | Novartis AG (CH) | 2000-05-10 | — | — | EP | claimed |
| WO-1999002497-A2 | PYRIDINE DERIVATIVES | NOVARTIS AG (CH) | 1999-01-21 | — | — | WO | claimed |
| EP-0998459-B1 | PYRIDINE DERIVATIVES | NOVARTIS AG (CH) | 2008-04-23 | — | — | EP | disclosed |