Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4711486 | 0.88 | GRM5 (0.46) | GRM5 | |
| SCHEMBL4711268 | 0.85 | GRM5 (0.43) | GRM5 | |
| SCHEMBL4713592 | 0.84 | GRM5 (0.44) | GRM5 | |
| SCHEMBL4712463 | 0.79 | GRM5 (0.49) | GRM5 | |
| SCHEMBL4711597 | 0.76 | GRM5 (0.44) | GRM5 | |
| SCHEMBL4710798 | 0.71 | GRM5 (0.54) | GRM5 | |
| SCHEMBL4710432 | 0.69 | GRM5 (0.53) | GRM5 | |
| SCHEMBL4713709 | 0.66 | GRM5 (0.66) | GRM5 | |
| SCHEMBL4710493 | 0.64 | GRM5 (0.60) | GRM5 | |
| SCHEMBL4871735 | 0.64 | GRM5 (0.54) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0998459-B1 | PYRIDINE DERIVATIVES | NOVARTIS AG (CH) | 2008-04-23 | — | — | EP | claimed |