Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17139814 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TSHRL3MBTL1CYP2C9MAPT | |
| SCHEMBL4714435 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TSHRL3MBTL1CYP2C9MAPT | |
| SCHEMBL238244 | 0.88 | ALDH1A1 (0.53) | ALDH1A1TSHRL3MBTL1CYP2C9MAPT | |
| SCHEMBL238243 | 0.88 | ALDH1A1 (0.53) | ALDH1A1TSHRL3MBTL1CYP2C9MAPT | |
| SCHEMBL238242 | 0.88 | ALDH1A1 (0.53) | ALDH1A1TSHRL3MBTL1CYP2C9MAPT | |
| SCHEMBL8783520 | 0.85 | ALDH1A1 (0.46) | ALDH1A1TSHRL3MBTL1CYP2C9MAPT | |
| SCHEMBL4959620 | 0.85 | ALDH1A1 (0.46) | ALDH1A1TSHRL3MBTL1CYP2C9MAPT | |
| SCHEMBL4959625 | 0.85 | ALDH1A1 (0.46) | ALDH1A1TSHRL3MBTL1CYP2C9MAPT | |
| SCHEMBL27578519 | 0.84 | THRB (0.50) | ALDH1A1TSHRL3MBTL1CYP2C9MAPT | |
| SCHEMBL2115865 | 0.83 | ALDH1A1 (0.61) | ALDH1A1TSHRL3MBTL1CYP2C9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110914263-A | Substituted bicyclic heterocyclic compounds as NADPH oxidase inhibitors | 格兰马克药品股份有限公司 | 2020-03-24 | — | — | CN | disclosed |
| EP-1622903-B1 | CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | PFIZER PROD INC (US) | 2008-10-01 | — | — | EP | disclosed |
| EP-1622903-A1 | CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | Pfizer Products Inc. (US) | 2006-02-08 | — | — | EP | disclosed |
| WO-2004094421-A1 | CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2004-11-04 | — | — | WO | disclosed |
| US-20040214856-A1 | Cannabinoid receptor ligands and uses thereof | PFIZER INC | 2004-10-28 | — | — | US | disclosed |
| CN-1483320-A | Heterocyclic ring contained methylamine cyanoacrylate compound and weeding activity | 南开大学 | 2004-03-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040214856-A1 | Cannabinoid receptor ligands and uses thereof | CNR1, CNR2, GPR18 | ALDH1A1 1920/4885TSHR 524/4885L3MBTL1 3805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.