Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4019344 | 0.81 | SMN1; SMN2 (0.49) | SMN1; SMN2KMT2AMEN1TSHRHTT | |
| SCHEMBL4715831 | 0.78 | TSHR (0.60) | SMN1; SMN2KMT2AMEN1TSHRHTT | |
| SCHEMBL4714343 | 0.76 | CASR (0.40) | SMN1; SMN2KMT2AMEN1TSHRHTT | |
| SCHEMBL4714622 | 0.75 | TSHR (0.56) | SMN1; SMN2KMT2AMEN1TSHRHTT | |
| SCHEMBL1856043 | 0.75 | SMN1; SMN2 (0.56) | SMN1; SMN2KMT2AMEN1TSHRHTT | |
| SCHEMBL4715815 | 0.73 | KMT2A (0.71) | SMN1; SMN2KMT2AMEN1TSHRHTT | |
| SCHEMBL5048888 | 0.73 | SMN1; SMN2 (0.53) | SMN1; SMN2KMT2AMEN1TSHRHTT | |
| SCHEMBL4715407 | 0.72 | SMN1; SMN2 (0.69) | SMN1; SMN2KMT2AMEN1TSHRHTT | |
| SCHEMBL4715813 | 0.72 | KMT2A (0.69) | SMN1; SMN2KMT2AMEN1TSHRHTT | |
| SCHEMBL27583581 | 0.71 | CYP2D6 (0.61) | SMN1; SMN2KMT2AMEN1TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1986637-A1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS | Laboratoires Serono SA (CH) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007093557-A1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS | LABORATOIRES SERONO S.A. (CH) | 2007-08-23 | — | — | WO | disclosed |