Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.44 |
| ▸ | BACE1 | P56817 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4714345 | 0.85 | LMNA (0.43) | BCHEBACE1LMNAPOLBMAPT | |
| SCHEMBL1852522 | 0.84 | TRPM8 (0.43) | BCHELMNARAB9AMEN1KMT2A | |
| SCHEMBL5040032 | 0.84 | ERBB2 (0.42) | LMNARAB9ATRPV1POLBMAPT | |
| SCHEMBL4717989 | 0.82 | MEN1 (0.47) | LMNARAB9ATRPV1POLBMAPT | |
| SCHEMBL4714650 | 0.82 | MEN1 (0.47) | LMNARAB9ATRPV1POLBMAPT | |
| SCHEMBL5047436 | 0.82 | MAPT (0.36) | LMNAPOLBMAPTMEN1KMT2A | |
| SCHEMBL4712382 | 0.79 | CCR1 (0.41) | BCHELMNATRPV1POLBMAPT | |
| SCHEMBL4711910 | 0.78 | MAPT (0.40) | BCHELMNARAB9ATRPV1POLB | |
| SCHEMBL5039556 | 0.77 | CAPN1 (0.38) | LMNAPOLBMEN1KMT2AELANE | |
| SCHEMBL5047519 | 0.72 | CASR (0.39) | LMNAPOLBMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | claimed |