Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 14/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4712862 | 0.83 | TP53 (0.46) | GRM5CYP3A4 | |
| SCHEMBL4715310 | 0.82 | HSD11B1 (0.56) | — | |
| SCHEMBL4713917 | 0.80 | GRM5 (0.41) | GRM5CYP3A4 | |
| SCHEMBL4715216 | 0.80 | GRM5 (0.51) | GRM5 | |
| SCHEMBL7262698 | 0.79 | GRM5 (0.47) | GRM5 | |
| SCHEMBL30478166 | 0.76 | RXFP1 (0.43) | HRH4 | |
| SCHEMBL4711712 | 0.75 | TSHR (0.50) | GRM5CYP3A4 | |
| Hydrochloric Acid SCHEMBL20524495 | 0.69 | PARP1 (0.48) | HRH4 | |
| SCHEMBL4710584 | 0.69 | GRM5 (0.52) | GRM5 | |
| SCHEMBL4712558 | 0.69 | GRM5 (0.65) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0998459-B1 | PYRIDINE DERIVATIVES | NOVARTIS AG (CH) | 2008-04-23 | — | — | EP | disclosed |