SCHEMBL4714749

SCHEMBL4714749

O=[N+]([O-])c1c(S)cccc1Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.43
TDP1 Q9NUW8 4/20 0.43
ALDH1A1 P00352 3/20 0.43
GRIN2D O15399 1/20 0.41
GRIN3B O60391 1/20 0.41
GRIN1 Q05586 1/20 0.41
GRIN2A Q12879 1/20 0.41
GRIN2B Q13224 1/20 0.41
GRIN2C Q14957 1/20 0.41
GRIN3A Q8TCU5 1/20 0.41
HSP90AA1 P07900 1/20 0.41
GPR35 Q9HC97 1/20 0.38
HPGD P15428 1/20 0.38
TLR8 Q9NR97 1/20 0.38
LMNA P02545 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
HSD17B10 Q99714 1/20 0.36
MAPK1 P28482 1/20 0.35
CYP3A4 P08684 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28145873 0.98 TSHR (0.42) TSHRTDP1ALDH1A1GRIN2DGRIN3B
SCHEMBL28145865 0.98 TSHR (0.42) TSHRTDP1ALDH1A1GRIN2DGRIN3B
Water SCHEMBL8128983 0.94 TSHR (0.39) TSHRTDP1ALDH1A1GRIN2DGRIN3B
SCHEMBL670917 0.84 TSHR (0.58) TSHRTDP1ALDH1A1GRIN2DGRIN3B
SCHEMBL29763129 0.77 TSHR (0.59) TSHRTDP1ALDH1A1GPR35HPGD
SCHEMBL942997 0.77 TSHR (0.59) TSHRTDP1ALDH1A1GPR35MEN1
SCHEMBL41402 0.77 TSHR (0.59) TSHRTDP1ALDH1A1GPR35HPGD
SCHEMBL8129828 0.77 TSHR (0.59) TSHRTDP1ALDH1A1GPR35MEN1
SCHEMBL11328561 0.77 TSHR (0.45) TSHRTDP1ALDH1A1GRIN2DGRIN3B
SCHEMBL28285744 0.77 ALDH1A1 (0.50) TSHRTDP1ALDH1A1GRIN2DGRIN3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119219534-B Synthesis method and application of o-amino disulfide and benazolin ethyl ester key intermediate 4-chlorobenzothiazole 鄂尔多斯应用技术学院 2025-04-08 CN claimed
CN-119219534-A Synthesis method and application of o-amino disulfide and benazolin ethyl ester key intermediate 4-chlorobenzothiazole 鄂尔多斯应用技术学院 2024-12-31 CN claimed
CN-119219534-B Synthesis method and application of o-amino disulfide and benazolin ethyl ester key intermediate 4-chlorobenzothiazole 鄂尔多斯应用技术学院 2025-04-08 CN disclosed
CN-119219534-A Synthesis method and application of o-amino disulfide and benazolin ethyl ester key intermediate 4-chlorobenzothiazole 鄂尔多斯应用技术学院 2024-12-31 CN disclosed
CN-103418115-B Golf DUNLOP SPORTS CO., LTD. (JP) 2016-05-11 CN disclosed
CN-103418116-B Golf DUNLOP SPORTS CO., LTD. (JP) 2016-05-04 CN disclosed
CN-103372285-B Golf DUNLOP SPORTS CO., LTD. (JP) 2016-04-20 CN disclosed
CN-105381573-A GOLF BALL DUNLOP SPORTS CO LTD 2016-03-09 CN disclosed
CN-103446722-B Golf DUNLOP SPORTS CO., LTD. (JP) 2016-02-17 CN disclosed
CN-103446721-B Golf DUNLOP SPORTS CO., LTD. (JP) 2016-02-17 CN disclosed
CN-103446723-B Golf DUNLOP SPORTS CO., LTD. (JP) 2015-11-18 CN disclosed
CN-103418115-A Golf ball DUNLOP SPORTS CO LTD 2013-12-04 CN disclosed
EP-1877401-A2 NOVEL COMPOUNDS USEFUL FOR BRADYKININ B1 RECEPTOR ANTAGONISM Elan Pharmaceuticals Inc. (US) 2008-01-16 EP disclosed
US-20070032475-A1 Novel compounds useful for bradykinin B1 receptor antagonism ELAN PHARMACEUTICALS, INC. 2007-02-08 US disclosed
US-20070032475-A1 Novel compounds useful for bradykinin B1 receptor antagonism ELAN PHARMACEUTICALS, INC. 2007-02-08 US disclosed
US-20070032475-A1 Novel compounds useful for bradykinin B1 receptor antagonism ELAN PHARMACEUTICALS, INC. 2007-02-08 US disclosed
WO-2006113140-A2 NOVEL COMPOUNDS USEFUL FOR BRADYKININ B1 RECEPTOR ANTAGONISM ELAN PHARMACEUTICALS, INC. (US) 2006-10-26 WO disclosed
US-4203897-A Penam derivatives FUJISAWA PHARMACEUTICAL COMPANY, LIMITED (JP) 1980-05-20 US disclosed
US-4084049-A CEPHALOSPORIN ANTIBIOTICS FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1978-04-11 US disclosed
US-3954732-A BACTERICIDAL PENICILLINS FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070032475-A1 Novel compounds useful for bradykinin B1 receptor antagonism BDKRB1, BDKRB2, NPBWR1 TSHR 1458/4885TDP1 3161/4885ALDH1A1 3073/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.