Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | TOP2A | P11388 | 8/20 | 0.56 |
| ▸ | TOP2B | Q02880 | 8/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CLK2 | P49760 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Heptane SCHEMBL8861899 | 0.91 | KDM4E (0.52) | KDM4ECYP1A2SMN1; SMN2TOP2ATOP2B | |
| SCHEMBL5443905 | 0.87 | TOP2A (0.61) | KDM4ECYP1A2SMN1; SMN2TOP2ATOP2B | |
| SCHEMBL4714330 | 0.85 | KDM4E (0.52) | KDM4ECYP1A2SMN1; SMN2TOP2ATOP2B | |
| SCHEMBL29473541 | 0.85 | KDM4E (0.52) | KDM4ECYP1A2SMN1; SMN2TOP2ATOP2B | |
| SCHEMBL4714327 | 0.85 | KDM4E (0.52) | KDM4ECYP1A2SMN1; SMN2TOP2ATOP2B | |
| SCHEMBL6217925 | 0.85 | TOP2A (0.61) | KDM4ECYP1A2SMN1; SMN2TOP2ATOP2B | |
| SCHEMBL4713233 | 0.85 | KDM4E (0.60) | KDM4ECYP1A2SMN1; SMN2TOP2ATOP2B | |
| SCHEMBL6217009 | 0.84 | ALDH1A1 (0.60) | KDM4ECYP1A2SMN1; SMN2TOP2ATOP2B | |
| SCHEMBL10582892 | 0.82 | KDM4E (0.52) | KDM4ECYP1A2SMN1; SMN2TOP2ATOP2B | |
| SCHEMBL8521029 | 0.82 | TOP2A (0.61) | KDM4ECYP1A2SMN1; SMN2TOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1262477-B1 | ANTI-ACID-FAST BACTERIAL AGENTS CONTAINING PYRIDONECARBOXYLIC ACIDS AS THE ACTIVE INGREDIENT | DAIICHI SANKYO CO LTD (JP) | 2008-09-03 | — | — | EP | claimed |
| US-20030119848-A1 | Anti acid-fast bacterial agent containing pyridonecarboxylic acids as active ingredient | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-06-26 | — | — | US | claimed |
| EP-1262477-A1 | ANTI-ACID-FAST BACTERIAL AGENTS CONTAINING PYRIDONECARBOXYLIC ACIDS AS THE ACTIVE INGREDIENT | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2002-12-04 | — | — | EP | claimed |
| US-20230218726-A1 | TREATMENT OF VIRAL CONJUNCTIVITIS | OKOGEN, INC. | 2023-07-13 | — | — | US | disclosed |
| EP-4138882-A1 | TREATMENT OF VIRAL CONJUNCTIVITIS | Okogen, Inc. (US) | 2023-03-01 | — | — | EP | disclosed |
| EP-1262477-B1 | ANTI-ACID-FAST BACTERIAL AGENTS CONTAINING PYRIDONECARBOXYLIC ACIDS AS THE ACTIVE INGREDIENT | DAIICHI SANKYO CO LTD (JP) | 2008-09-03 | — | — | EP | disclosed |
| US-7176313-B2 | Anti acid-fast bacterial agent containing pyridonecarboxylic acids as active ingredient | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-02-13 | — | — | US | disclosed |
| US-20030119848-A1 | Anti acid-fast bacterial agent containing pyridonecarboxylic acids as active ingredient | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-06-26 | — | — | US | disclosed |
| EP-1262477-A1 | ANTI-ACID-FAST BACTERIAL AGENTS CONTAINING PYRIDONECARBOXYLIC ACIDS AS THE ACTIVE INGREDIENT | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2002-12-04 | — | — | EP | disclosed |
| CN-1044118-C | 7-isoindolinyl-quinolone derivatives and process for their preparation | BAYER AG (DE) | 1999-07-14 | — | — | CN | disclosed |
| CN-1189494-A | Substituted isoazalene compound | BAYER AG (DE) | 1998-08-05 | — | — | CN | disclosed |
| US-5250705-A | Salt formation with tartaric acid; treatment with base; deprotection | SHIONOGI & CO., LTD. (JP) | 1993-10-05 | — | — | US | disclosed |
| EP-0487030-A2 | Process of optical resolution for the preparation of an optically active cyclic amine | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1992-05-27 | — | — | EP | disclosed |
| EP-0226961-B1 | 5-AMINO AND 5-HYDROXY-6,8-DIFLUOROQUINOLONES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1991-06-12 | — | — | EP | disclosed |
| US-4977154-A | 7-PIPERAZINE DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 1990-12-11 | — | — | US | disclosed |
| EP-0226961-A1 | 5-Amino and 5-hydroxy-6,8-difluoroquinolones as antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1987-07-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030119848-A1 | Anti acid-fast bacterial agent containing pyridonecarboxylic acids as active ingredient | PGD, PPA1, FASTKD1 | KDM4E 3677/4885CYP1A2 2156/4885SMN1; SMN2 3603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.