Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1797802 | 0.86 | PTGES (0.48) | PTGESMEN1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL1801358 | 0.82 | BCHE (0.53) | MEN1KMT2AACHEBCHEMAPT | |
| SCHEMBL1799798 | 0.81 | ACHE (0.43) | PTGESMEN1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL1801270 | 0.80 | HDAC1 (0.43) | PTGESMEN1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL1800052 | 0.77 | HDAC3 (0.46) | PTGESMEN1KMT2ATAS2R14ACHE | |
| SCHEMBL15265872 | 0.76 | BCHE (0.48) | PTGESMEN1KMT2ATAS2R14HPGD | |
| SCHEMBL27761564 | 0.76 | MEN1 (0.39) | PTGESMEN1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL1802321 | 0.76 | HDAC1 (0.39) | PTGESMEN1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL1798300 | 0.75 | HDAC1 (0.42) | PTGESCYP4F2CYP4A11L3MBTL1MAPT | |
| SCHEMBL1799921 | 0.74 | ITGA4 (0.43) | MEN1KMT2ACYP4F2CYP4A11ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1996566-A1 | BEZOTHIAZOL DERIVATIVES AS BETA2 ADRENORECEPTOR AGONISTS | AstraZeneca AB (SE) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007106016-A1 | BEZOTHIAZOL DERIVATIVES AS BETA2 ADRENORECEPTOR AGONISTS | ASTRAZENECA AB (SE) | 2007-09-20 | — | — | WO | disclosed |