Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GUSB | P08236 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4714003 | 0.86 | ALDH1A1 (0.53) | ALDH1A1HTTNPSR1POLBSMN1; SMN2 | |
| SCHEMBL4715421 | 0.85 | ALDH1A1 (0.46) | ALDH1A1HTTNPSR1POLBGUSB | |
| SCHEMBL5048907 | 0.72 | GUSB (0.44) | GUSBEPHX2AKR1C3 | |
| SCHEMBL11888616 | 0.72 | SMN1; SMN2 (0.64) | ALDH1A1HTTNPSR1SMN1; SMN2 | |
| SCHEMBL3699519 | 0.72 | KMT2A (0.57) | ALDH1A1HTTNPSR1SMN1; SMN2L3MBTL1 | |
| SCHEMBL4902642 | 0.71 | LMNA (0.60) | ALDH1A1POLBSMN1; SMN2TBXA2RTBXAS1 | |
| SCHEMBL4714000 | 0.70 | ALDH1A1 (0.46) | ALDH1A1HTTNPSR1SMN1; SMN2 | |
| SCHEMBL4025022 | 0.70 | TSHR (0.49) | ALDH1A1HTTPOLBSMN1; SMN2EPHX2 | |
| SCHEMBL4025020 | 0.70 | TSHR (0.49) | ALDH1A1HTTSMN1; SMN2EPHX2L3MBTL1 | |
| SCHEMBL4903809 | 0.70 | ALDH1A1 (0.55) | ALDH1A1POLBSMN1; SMN2TBXA2RTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1986637-A1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS | Laboratoires Serono SA (CH) | 2008-11-05 | — | — | EP | claimed |
| WO-2007093557-A1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS | LABORATOIRES SERONO S.A. (CH) | 2007-08-23 | — | — | WO | claimed |