Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | IL1RN | P18510 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4716103 | 0.91 | MEN1 (0.51) | AGTR1L3MBTL1TSHRMEN1KMT2A | |
| SCHEMBL4716303 | 0.89 | MEN1 (0.51) | AGTR1TSHRPOLBNPC1MEN1 | |
| SCHEMBL4713963 | 0.89 | LMNA (0.52) | AGTR1L3MBTL1NPC1CASP6MEN1 | |
| SCHEMBL4716298 | 0.89 | MCOLN3 (0.54) | AGTR1L3MBTL1TSHRPOLBCASP6 | |
| SCHEMBL4714628 | 0.88 | AGTR1 (0.52) | AGTR1L3MBTL1TSHRPOLBNPC1 | |
| SCHEMBL4715768 | 0.88 | MAPT (0.56) | L3MBTL1POLBMEN1KMT2AMAPT | |
| SCHEMBL4713545 | 0.88 | TSHR (0.57) | L3MBTL1TSHRPOLBCASP6MEN1 | |
| SCHEMBL4716022 | 0.87 | ALDH1A1 (0.55) | AGTR1L3MBTL1TSHRMEN1KMT2A | |
| SCHEMBL4716372 | 0.85 | AGTR1 (0.52) | AGTR1L3MBTL1POLBNPC1MEN1 | |
| SCHEMBL4714267 | 0.85 | TSHR (0.54) | L3MBTL1TSHRPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615904-B1 | SUBSTITUTED BENZOSULPHONAMIDES AS POTENTIATORS OF GLUTAMATE RECEPTORS | ASTRAZENECA AB (SE) | 2008-02-27 | — | — | EP | disclosed |
| US-20070021606-A1 | Therapeutic compounds | ASTRAZENECA AB (SE) | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021606-A1 | Therapeutic compounds | GRIN1, GRIN3A, GRM2 | AGTR1 612/4885L3MBTL1 4874/4885TSHR 685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.