Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | PNP | P00491 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4719204 | 0.87 | MCHR1 (0.39) | DHFRTSHRHTTMEN1SLC22A1 | |
| SCHEMBL3221311 | 0.85 | MCHR1 (0.49) | ADORA2AADORA1ADORA3ADCY10LTA4H | |
| SCHEMBL4718160 | 0.81 | ADCY10 (0.46) | ADORA2AADORA1ADORA3ADCY10LTA4H | |
| SCHEMBL4715898 | 0.81 | TAAR1 (0.41) | ADORA2AADORA1ADORA3ADCY10LTA4H | |
| SCHEMBL4717995 | 0.80 | PDE10A (0.46) | ADORA2AADORA1ADORA3ADCY10LTA4H | |
| SCHEMBL3218795 | 0.78 | TLR8 (0.62) | ADORA2AADORA1ADORA3ADCY10LTA4H | |
| SCHEMBL3196286 | 0.77 | TLR8 (0.49) | ADORA2AADORA1ADORA3ADCY10LTA4H | |
| SCHEMBL3206489 | 0.76 | AKT1 (0.43) | ADORA2AADORA1ADORA3ADCY10LTA4H | |
| SCHEMBL3220325 | 0.76 | PLA2G2A (0.46) | ADORA2AADORA1ADORA3ADCY10LTA4H | |
| SCHEMBL3208174 | 0.76 | ALDH1A1 (0.53) | ADORA2AADORA1ADORA3ADCY10LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1917245-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS BINDING PARTNERS FOR 5-HT5 RECEPTORS | Abbott GmbH & Co. KG (DE) | 2008-05-07 | — | — | EP | disclosed |
| WO-2007022946-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS BINDING PARTNERS FOR 5-HT5 RECEPTORS | ABBOTT GMBH & CO. KG (DE) | 2007-03-01 | — | — | WO | disclosed |