Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLD1 | Q13393 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | USP2 | O75604 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29400889 | 0.83 | PLD1 (1.00) | PLD1ALDH1A1HSD17B10HPGDCYP3A4 | |
| SCHEMBL7900 | 0.83 | PLD1 (1.00) | PLD1ALDH1A1HSD17B10HPGDCYP3A4 | |
| SCHEMBL893565 | 0.83 | PLD1 (1.00) | PLD1ALDH1A1HSD17B10HPGDCYP3A4 | |
| Bromide SCHEMBL11807389 | 0.81 | PLD1 (0.96) | PLD1ALDH1A1HSD17B10HPGDCYP3A4 | |
| Ammonia Solution, Strong SCHEMBL17926100 | 0.81 | PLD1 (0.96) | PLD1ALDH1A1HSD17B10HPGDCYP3A4 | |
| Piperazine SCHEMBL27920772 | 0.81 | PLD1 (0.96) | PLD1ALDH1A1HSD17B10HPGDCYP3A4 | |
| Hydrochloric Acid SCHEMBL6349557 | 0.81 | PLD1 (0.96) | PLD1ALDH1A1HSD17B10HPGDCYP3A4 | |
| Hydrochloric Acid SCHEMBL4165242 | 0.81 | PLD1 (0.96) | PLD1ALDH1A1HSD17B10HPGDCYP3A4 | |
| Hydrochloric Acid SCHEMBL27481639 | 0.81 | PLD1 (0.96) | PLD1ALDH1A1HSD17B10HPGDCYP3A4 | |
| Ammonia Solution, Strong SCHEMBL8745498 | 0.81 | PLD1 (0.96) | PLD1ALDH1A1HSD17B10HPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070032475-A1 | Novel compounds useful for bradykinin B1 receptor antagonism | ELAN PHARMACEUTICALS, INC. | 2007-02-08 | — | — | US | claimed |
| EP-1877401-A2 | NOVEL COMPOUNDS USEFUL FOR BRADYKININ B1 RECEPTOR ANTAGONISM | Elan Pharmaceuticals Inc. (US) | 2008-01-16 | — | — | EP | disclosed |
| US-20070032475-A1 | Novel compounds useful for bradykinin B1 receptor antagonism | ELAN PHARMACEUTICALS, INC. | 2007-02-08 | — | — | US | disclosed |
| WO-2006113140-A2 | NOVEL COMPOUNDS USEFUL FOR BRADYKININ B1 RECEPTOR ANTAGONISM | ELAN PHARMACEUTICALS, INC. (US) | 2006-10-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032475-A1 | Novel compounds useful for bradykinin B1 receptor antagonism | BDKRB1, BDKRB2, NPBWR1 | PLD1 1317/4885ALDH1A1 3073/4885HSD17B10 2492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.