Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4716298 | 0.87 | MCOLN3 (0.54) | ALDH1A1KMT2APOLBMAPTAGTR1 | |
| SCHEMBL4716394 | 0.83 | CNR1 (0.52) | CNR1ALDH1A1KMT2APOLBMAPT | |
| SCHEMBL4715768 | 0.83 | MAPT (0.56) | ALDH1A1KMT2APOLBMAPTNPSR1 | |
| SCHEMBL4716303 | 0.82 | MEN1 (0.51) | ALDH1A1KMT2APOLBMAPTAGTR1 | |
| SCHEMBL4716188 | 0.82 | AGTR1 (0.53) | ALDH1A1KMT2APOLBMAPTAGTR1 | |
| SCHEMBL4713091 | 0.82 | ALDH1A1 (0.54) | ALDH1A1KMT2APOLBL3MBTL1NPC1 | |
| SCHEMBL4716103 | 0.81 | MEN1 (0.51) | ALDH1A1KMT2AMAPTAGTR1NPSR1 | |
| SCHEMBL4717893 | 0.81 | MAPK1 (0.47) | ALDH1A1KMT2APOLBMAPTNPSR1 | |
| SCHEMBL4716686 | 0.80 | ATM (0.47) | MAPT | |
| SCHEMBL4715371 | 0.79 | KMT2A (0.44) | CNR1ALDH1A1KMT2APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615904-B1 | SUBSTITUTED BENZOSULPHONAMIDES AS POTENTIATORS OF GLUTAMATE RECEPTORS | ASTRAZENECA AB (SE) | 2008-02-27 | — | — | EP | claimed |