Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | TPH1 | P17752 | 2/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3316938 | 0.99 | TPH1 (0.42) | ALDH1A1RAB9AKMT2APKMTPH1 | |
| SCHEMBL4035263 | 0.90 | TPH1 (0.42) | ALDH1A1KMT2APKMTPH1SLC7A5 | |
| SCHEMBL4035478 | 0.90 | TPH1 (0.42) | ALDH1A1KMT2APKMTPH1SLC7A5 | |
| SCHEMBL3877275 | 0.90 | TPH1 (0.42) | ALDH1A1KMT2APKMTPH1SLC7A5 | |
| SCHEMBL3278235 | 0.86 | ALDH1A1 (0.42) | ALDH1A1PKMTPH1SLC7A5KDM4E | |
| SCHEMBL18554069 | 0.83 | SLC7A5 (0.57) | KMT2APKMSLC7A5KDM4EUSP2 | |
| SCHEMBL3751437 | 0.83 | KDM4E (0.49) | ALDH1A1TPH1SLC7A5KDM4EUSP2 | |
| SCHEMBL4717979 | 0.82 | SMN1; SMN2 (0.43) | ALDH1A1RAB9AKMT2APKMTPH1 | |
| SCHEMBL7960935 | 0.82 | SLC7A5 (0.48) | ALDH1A1PKMTPH1SLC7A5PTGS1 | |
| Hydrochloric Acid SCHEMBL20474572 | 0.82 | SLC7A5 (0.55) | KMT2APKMSLC7A5KDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558600-B1 | SELECTED CGRP ANTAGONISTS, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENT | BOEHRINGER INGELHEIM PHARMA (DE) | 2008-05-07 | — | — | EP | disclosed |
| EP-1558600-A1 | SELECTED CGRP ANTAGONISTS, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENT | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2005-08-03 | — | — | EP | disclosed |
| WO-2004037810-A1 | SELECTED CGRP ANTAGONISTS, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENT | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-05-06 | — | — | WO | disclosed |