Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 7/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | LSS | P48449 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4712466 | 0.79 | ACHE (0.50) | ACHEF10HTR1ADRD4 | |
| SCHEMBL3440253 | 0.78 | ACHE (0.63) | ACHE | |
| SCHEMBL4716488 | 0.73 | CD274 (0.50) | ACHENAMPTF10 | |
| SCHEMBL4717344 | 0.70 | BDKRB1 (0.51) | NAMPTF10 | |
| SCHEMBL785872 | 0.68 | ACHE (0.46) | ACHEF10LSS | |
| SCHEMBL12043784 | 0.67 | ACHE (1.00) | ACHE | |
| SCHEMBL4713068 | 0.66 | BDKRB1 (0.47) | NAMPTF10 | |
| SCHEMBL8125687 | 0.66 | TPSAB1 (0.50) | F10HTR1ALSS | |
| SCHEMBL5177805 | 0.66 | MAPT (0.44) | ACHEF10LSS | |
| SCHEMBL786054 | 0.65 | ACHE (0.47) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1877401-A2 | NOVEL COMPOUNDS USEFUL FOR BRADYKININ B1 RECEPTOR ANTAGONISM | Elan Pharmaceuticals Inc. (US) | 2008-01-16 | — | — | EP | disclosed |
| WO-2006113140-A2 | NOVEL COMPOUNDS USEFUL FOR BRADYKININ B1 RECEPTOR ANTAGONISM | ELAN PHARMACEUTICALS, INC. (US) | 2006-10-26 | — | — | WO | disclosed |