Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CENPE | Q02224 | 3/20 | 0.45 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3233694 | 0.83 | CENPE (0.52) | CENPEKIFC1P2RX3S1PR1WNT3A | |
| SCHEMBL4722508 | 0.83 | CENPE (0.45) | CENPEKIFC1P2RX3MAP4K4MINK1 | |
| SCHEMBL4719622 | 0.79 | CENPE (0.38) | CENPEKIFC1P2RX3MAP4K4MINK1 | |
| SCHEMBL3221828 | 0.78 | CENPE (0.46) | CENPEKIFC1KMT2AWNT3A | |
| SCHEMBL3233700 | 0.75 | CENPE (0.43) | CENPEKMT2ASMN1; SMN2WNT3A | |
| SCHEMBL4718279 | 0.73 | CENPE (0.46) | CENPEKIFC1P2RX3MAP4K4MINK1 | |
| SCHEMBL3233756 | 0.72 | CENPE (0.47) | CENPEKIFC1S1PR1 | |
| SCHEMBL3220019 | 0.71 | CENPE (0.48) | CENPEKIFC1WNT3A | |
| SCHEMBL3220035 | 0.71 | CENPE (0.48) | CENPEKIFC1WNT3A | |
| SCHEMBL3223157 | 0.71 | CENPE (0.52) | CENPEKIFC1MAP4K4MINK1S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1951719-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-08-06 | — | — | EP | claimed |
| WO-2007056469-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-18 | — | — | WO | claimed |