SCHEMBL471778

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10053097	0.87	PTPN1 (0.33)	PTPN1PTPN2PTPRFMAPTPTPN6
	SCHEMBL18288929	0.76	MAPT (0.44)	PTPN1PTPN2PTPRFMAPTCHRNA7
	SCHEMBL10053742	0.75	SMN1; SMN2 (0.40)	PTPN1PTPN2PTPRFCHRNA7SCN1A
	SCHEMBL1900169	0.74	PTPN1 (0.39)	PTPN1PTPN2PTPRFSCN1ASCN2A
	SCHEMBL27834872	0.73	STS (0.40)	PTPN1PTPN2PTPRFMAPTCHRNA7
	SCHEMBL1899821	0.72	PTPN1 (0.40)	PTPN1PTPN2PTPRFMAPTCHRNA7
	SCHEMBL1900558	0.72	POLB (0.40)	PTPN1PTPN2PTPRFMAPTCHRNA7
	SCHEMBL9814417	0.72	PTPN1 (0.38)	PTPN1PTPN2PTPRFPTPN6PTPN11
	SCHEMBL16273220	0.70	TSHR (0.49)	PTPN1PTPN2PTPRFCHRNA7SCN1A
	SCHEMBL471779	0.70	SMN1; SMN2 (0.38)	SCN1ASCN2ASCN3ASMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.