SCHEMBL471779

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10053102	0.95	TAS1R3 (0.35)	SMN1; SMN2SCN1ASCN2ASCN3ATAS1R3
	SCHEMBL472300	0.89	CYP2D6 (0.33)	SMN1; SMN2MEN1KMT2AALDH1A1CYP2D6
	SCHEMBL10021856	0.88	CYP2D6 (0.32)	SMN1; SMN2MEN1KMT2AALDH1A1CYP2D6
	SCHEMBL10021857	0.87	ALDH1A1 (0.32)	SMN1; SMN2MEN1KMT2AALDH1A1CYP2D6
	SCHEMBL10021861	0.87	ALDH1A1 (0.32)	SMN1; SMN2MEN1KMT2AALDH1A1CYP2D6
	SCHEMBL10021858	0.86	ALDH1A1 (0.38)	L3MBTL1MEN1KMT2AALDH1A1
	SCHEMBL10053742	0.86	SMN1; SMN2 (0.40)	SMN1; SMN2SCN1ASCN2ASCN3ATAS1R3
	SCHEMBL10053096	0.85	KDM2B (0.32)	MEN1KMT2AALDH1A1CYP2D6
	SCHEMBL17936646	0.82	SERPINE1 (0.38)	SMN1; SMN2SCN1ASCN2ASCN3AMEN1
	SCHEMBL20109663	0.81	POLB (0.46)	SMN1; SMN2SCN1ASCN2ASCN3AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.