Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.54 |
| ▸ | RELA | Q04206 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | PLK1 | P53350 | 1/20 | 0.53 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CHUK | O15111 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL255502 | 0.92 | L3MBTL1 (0.74) | L3MBTL1NR1H4RAB9ANFKB1NFKB2 | |
| Dimethylamine SCHEMBL7954889 | 0.87 | L3MBTL1 (0.67) | L3MBTL1NR1H4RAB9ANFKB1NFKB2 | |
| SCHEMBL13415301 | 0.82 | L3MBTL1 (0.69) | L3MBTL1NR1H4RAB9ANFKB1NFKB2 | |
| SCHEMBL6656268 | 0.79 | NR1H4 (0.68) | L3MBTL1NR1H4RAB9ANFKB1NFKB2 | |
| SCHEMBL13130238 | 0.79 | L3MBTL1 (1.00) | L3MBTL1RAB9ANPC1PLK1MAPT | |
| SCHEMBL1128734 | 0.77 | PLK1 (0.60) | L3MBTL1NR1H4RAB9ANFKB1NFKB2 | |
| SCHEMBL326978 | 0.76 | PLK1 (0.69) | L3MBTL1NR1H4RAB9ANFKB1NFKB2 | |
| SCHEMBL2967349 | 0.76 | L3MBTL1 (0.62) | L3MBTL1NR1H4RAB9ANFKB1NFKB2 | |
| SCHEMBL13167094 | 0.75 | L3MBTL1 (0.77) | L3MBTL1NR1H4RAB9ANFKB1NFKB2 | |
| SCHEMBL764971 | 0.75 | L3MBTL1 (0.77) | L3MBTL1RAB9ANPC1PLK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490367-B1 | IMIDAZOPYRIDINE DERIVATIVES AS KINASE INHIBITORS | GLAXO GROUP LTD (GB) | 2008-07-23 | — | — | EP | disclosed |