Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | PLK1 | P53350 | 1/20 | 0.58 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.58 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.53 |
| ▸ | TUBB | P07437 | 1/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.53 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.53 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.53 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.53 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.53 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.53 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.53 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL255502 | 0.94 | L3MBTL1 (0.74) | L3MBTL1PLK1NOTUMNR1H4NPC1 | |
| SCHEMBL4718445 | 0.87 | L3MBTL1 (0.65) | L3MBTL1PLK1NOTUMNR1H4NPC1 | |
| SCHEMBL13415301 | 0.83 | L3MBTL1 (0.69) | L3MBTL1PLK1NR1H4NPC1RAB9A | |
| SCHEMBL6656268 | 0.81 | NR1H4 (0.68) | L3MBTL1NR1H4NPC1RAB9ANFKB1 | |
| SCHEMBL13130238 | 0.80 | L3MBTL1 (1.00) | L3MBTL1PLK1NPC1RAB9ACA12 | |
| SCHEMBL7390745 | 0.79 | PLK1 (0.61) | L3MBTL1PLK1NR1H4NPC1RAB9A | |
| SCHEMBL2967349 | 0.78 | L3MBTL1 (0.62) | L3MBTL1PLK1NR1H4NPC1RAB9A | |
| SCHEMBL8311929 | 0.78 | L3MBTL1 (0.72) | L3MBTL1PLK1NPC1RAB9ATUBB4A | |
| Dimethylamine SCHEMBL7961743 | 0.78 | SMN1; SMN2 (0.67) | L3MBTL1NR1H4NPC1RAB9ANFKB1 | |
| SCHEMBL14520138 | 0.77 | TUBB4A (0.61) | L3MBTL1NOTUMNR1H4NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277872-B1 | ANTIISCHEMIC AGENTS; BRAIN DISORDERS | BOEHRINGER INGELHEIM KG (DE) | 2001-08-21 | — | — | US | disclosed |