Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.37 |
| ▸ | YES1 | P07947 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3593106 | 0.91 | TP53 (0.41) | MTNR1AMTNR1BPLA2G2ACNR1CNR2 | |
| SCHEMBL3590898 | 0.90 | PIN1 (0.39) | SERPINE1YES1KDRJAK3MEN1 | |
| SCHEMBL3603757 | 0.89 | ALDH1A1 (0.38) | YES1KDRJAK3PLA2G2AMEN1 | |
| SCHEMBL3599611 | 0.87 | YES1 (0.38) | YES1KDRJAK3PLA2G2AMEN1 | |
| SCHEMBL13254404 | 0.85 | MEN1 (0.44) | YES1KDRJAK3PLA2G2AGAA | |
| SCHEMBL3593102 | 0.85 | PDE4A (0.38) | CNR1CNR2GAAMEN1KMT2A | |
| SCHEMBL3605698 | 0.85 | PLA2G2A (0.39) | MTNR1AMTNR1BPLA2G2ACNR1CNR2 | |
| SCHEMBL3603503 | 0.82 | MEN1 (0.44) | GAAMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL3596002 | 0.82 | HTR2C (0.44) | GAAMEN1KMT2APDE4APDE4B | |
| SCHEMBL3603046 | 0.81 | ALDH1A1 (0.38) | CNR1CNR2MEN1KMT2AS1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1930320-A1 | NOVEL FUSED PYRROLE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2008-06-11 | — | — | EP | disclosed |