Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 15/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8636289 | 0.79 | SLC6A3 (0.53) | SLC6A3SLC6A2ACHESLC6A4 | |
| SCHEMBL18982990 | 0.77 | SLC6A3 (0.45) | SLC6A3SLC6A2ACHESLC6A4 | |
| SCHEMBL757145 | 0.75 | SLC6A3 (0.47) | SLC6A3SLC6A2ACHESLC6A4 | |
| SCHEMBL15876290 | 0.74 | SLC6A3 (0.41) | SLC6A3SLC6A2ACHESLC6A4 | |
| SCHEMBL2131145 | 0.74 | SLC6A3 (0.53) | SLC6A3SLC6A2ACHESLC6A4 | |
| SCHEMBL502662 | 0.73 | SLC6A3 (0.37) | SLC6A3SLC6A2ACHESLC6A4 | |
| SCHEMBL29868840 | 0.73 | SLC6A3 (0.49) | SLC6A3SLC6A2ACHESLC6A4ABCB1 | |
| SCHEMBL9269477 | 0.72 | SLC6A3 (0.39) | SLC6A3SLC6A2ACHESLC6A4 | |
| SCHEMBL9561660 | 0.71 | SLC6A3 (0.50) | SLC6A3SLC6A2ACHESLC6A4 | |
| SCHEMBL819039 | 0.71 | SLC6A3 (0.47) | SLC6A3SLC6A2ACHESLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |