Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 15/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2371417 | 0.95 | SLC6A3 (0.54) | SLC6A3SLC6A2SLC6A4ACHE | |
| SCHEMBL5607802 | 0.91 | SLC6A3 (0.44) | SLC6A3SLC6A2SLC6A4ACHE | |
| SCHEMBL8636289 | 0.91 | SLC6A3 (0.53) | SLC6A3SLC6A2SLC6A4ACHE | |
| SCHEMBL2131145 | 0.85 | SLC6A3 (0.53) | SLC6A3SLC6A2SLC6A4ACHE | |
| SCHEMBL252316 | 0.81 | DHODH (0.38) | SLC6A3SLC6A2SLC6A4DHODH | |
| SCHEMBL16817540 | 0.80 | SLC6A3 (0.50) | SLC6A3SLC6A2SLC6A4ACHE | |
| SCHEMBL5607056 | 0.80 | NPSR1 (0.46) | SLC6A3SLC6A2SLC6A4ACHE | |
| SCHEMBL11755388 | 0.80 | NPSR1 (0.46) | SLC6A3SLC6A2SLC6A4ACHE | |
| SCHEMBL11755378 | 0.80 | NPSR1 (0.46) | SLC6A3SLC6A2SLC6A4ACHE | |
| SCHEMBL252263 | 0.80 | DHODH (0.45) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250002470-A1 | NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | ZHEJIANG AIXPLORER BIOTECH CO., LTD. (CN) | 2025-01-02 | — | — | US | disclosed |
| EP-4421068-A1 | NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Zhejiang Aixplorer Biotech Co., Ltd. (CN) | 2024-08-28 | — | — | EP | disclosed |
| CN-116102535-A | Nitrogen-containing compound, preparation method and application thereof | 索智生物科技（浙江）有限公司 | 2023-05-12 | — | — | CN | disclosed |
| WO-2023066377-A1 | NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 索智生物科技（浙江）有限公司 | 2023-04-27 | — | — | WO | disclosed |
| WO-2023066377-A1 | NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 索智生物科技（浙江）有限公司 | 2023-04-27 | — | — | WO | disclosed |
| CN-108658762-A | A kind of synthetic method of alicyclic ring neighbour diester | 浙江凯普化工有限公司 | 2018-10-16 | — | — | CN | disclosed |
| US-9604977-B2 | Bicyclic thiophenylamide compounds | HOFFMAN-LA ROCHE INC. (US) | 2017-03-28 | — | — | US | disclosed |
| US-9353102-B2 | Non-annulated thiophenylamides | HOFFMANN-LA ROCHE INC. (US) | 2016-05-31 | — | — | US | disclosed |
| EP-2861574-B1 | NEW BICYCLIC THIOPHENYLAMIDE COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2016-04-20 | — | — | EP | disclosed |
| EP-2895481-A1 | NON-ANNULATED THIOPHENYLAMIDES AS INHIBITORS OF FATTY ACID BINDING PROTEINI(FABP) 4 AND/OR 5 | F. Hoffmann-La Roche AG (CH) | 2015-07-22 | — | — | EP | disclosed |
| US-20150183778-A1 | New non-annulated thiophenylamides | HOFFMANN-LA ROCHE INC. (US) | 2015-07-02 | — | — | US | disclosed |
| US-20150175594-A1 | NEW BICYCLIC THIOPHENYLAMIDE COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 2015-06-25 | — | — | US | disclosed |
| CN-104395301-A | New bicyclic thiophenylamide compounds | HOFFMANN LA ROCHE | 2015-03-04 | — | — | CN | disclosed |
| WO-2014040938-A1 | NON-ANNULATED THIOPHENYLAMIDES AS INHIBITORS OF FATTY ACID BINDING PROTEINI(FABP) 4 AND/OR 5 | F. HOFFMANN-LA ROCHE AG (CH) | 2014-03-20 | — | — | WO | disclosed |
| EP-0550019-A2 | Novel quinolone carboxylic acid derivatives and processes for preparing same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-07-07 | — | — | EP | disclosed |
| WO-1993008163-A1 | UNSATURATED AZABICYCLOAMINE COMPOUNDS AND PROCESSES FOR THE PREPARATION THEREOF | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-04-29 | — | — | WO | disclosed |
| EP-0537556-A1 | Unsaturated azabicycloamine compounds and processes for the preparation thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-04-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250002470-A1 | NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | NOD1, NLRP3, NLRP1 | SLC6A3 2102/4885SLC6A2 1020/4885SLC6A4 852/4885 |
| US-20150175594-A1 | NEW BICYCLIC THIOPHENYLAMIDE COMPOUNDS | NAT1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, BICRA | SLC6A3 1375/4885SLC6A2 2047/4885SLC6A4 1218/4885 |
| US-20150183778-A1 | New non-annulated thiophenylamides | NAT1, NCL, NTSR1 | SLC6A3 903/4885SLC6A2 1309/4885SLC6A4 584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.