SCHEMBL471948

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL471949	1.00	PTGS2 (0.83)	PTGS2MAOBSPRKDM4EALDH1A1
	N-Caffeoylserotonin SCHEMBL4294054	0.91	PTGS2 (1.00)	PTGS2MAOBSPRKDM4EALDH1A1
	N-Caffeoylserotonin SCHEMBL803616	0.91	PTGS2 (1.00)	PTGS2MAOBSPRKDM4EALDH1A1
	N-Caffeoylserotonin SCHEMBL30039282	0.91	PTGS2 (1.00)	PTGS2MAOBSPRKDM4EALDH1A1
	SCHEMBL10071695	0.90	MEN1 (0.72)	PTGS2MAOBALDH1A1CYP1A2MAPT
	N-P-Coumaroyl Serotonin SCHEMBL471922	0.88	MAOB (1.00)	PTGS2MAOBSPRKDM4EALDH1A1
	N-P-Coumaroyl Serotonin SCHEMBL471921	0.88	MAOB (1.00)	PTGS2MAOBSPRKDM4EALDH1A1
	N-P-Coumaroyl Serotonin SCHEMBL29594565	0.88	MAOB (1.00)	PTGS2MAOBSPRKDM4EALDH1A1
	N-Feruloyl Serotonin SCHEMBL1809357	0.87	PTGS2 (0.79)	PTGS2MAOBMEN1KMT2AACHE
	N-Feruloyl Serotonin SCHEMBL30037765	0.87	PTGS2 (0.79)	PTGS2MAOBMEN1KMT2AACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.