N-Feruloyl Serotonin

N-Feruloyl Serotonin

SCHEMBL1809357

COc1cc(C=CC(=O)NCCc2c[nH]c3ccc(O)cc23)ccc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.79
ACHE P22303 4/20 0.75
MAOB P27338 1/20 0.74
BCHE P06276 1/20 0.73
MEN1 O00255 3/20 0.72
KMT2A Q03164 3/20 0.72
TYR P14679 2/20 0.61
HDAC3 O15379 3/20 0.61
HDAC6 Q9UBN7 3/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
N-Feruloyl Serotonin SCHEMBL12063415 1.00 PTGS2 (0.79) PTGS2ACHEMAOBBCHEMEN1
N-Feruloyl Serotonin SCHEMBL30037765 1.00 PTGS2 (0.79) PTGS2ACHEMAOBBCHEMEN1
N-Isoferuloyl Serotonin SCHEMBL803830 0.93 PTGS2 (0.79) PTGS2ACHEMAOBBCHEMEN1
SCHEMBL10071694 0.92 ACHE (0.88) PTGS2ACHEMAOBBCHEMEN1
SCHEMBL803753 0.91 PTGS2 (0.76) PTGS2ACHEMAOBBCHEMEN1
N-Sinapoyl Serotonin SCHEMBL803240 0.90 MAOB (0.74) PTGS2ACHEMAOBBCHEMEN1
SCHEMBL4434094 0.90 ACHE (0.88) PTGS2ACHEMAOBBCHEMEN1
SCHEMBL10070987 0.90 ACHE (0.88) PTGS2ACHEMAOBBCHEMEN1
SCHEMBL31634290 0.90 ACHE (0.88) PTGS2ACHEMAOBBCHEMEN1
N-Caffeoylserotonin SCHEMBL803616 0.88 PTGS2 (1.00) PTGS2ACHEMAOBBCHEMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120201991-A Composition for improving skin wrinkles 株式会社LG生活健康 2025-06-24 CN claimed
WO-2024106669-A1 COMPOSITION FOR IMPROVING SKIN WRINKLES 주식회사 엘지생활건강 2024-05-23 WO claimed
WO-2024105703-A1 NOVEL OPHTHALMIC FORMULATION FERTIS INDIA PVT LTD (IN) 2024-05-23 WO claimed
EP-3253229-B1 PROCESS FOR THE FRACTIONATION OF SEEDS FROM OLEAGINOUS PLANTS. NOVAMONT SPA (IT) 2022-12-28 EP claimed
US-8309576-B2 Method of treating inflammatory bowel disease AJINOMOTO CO., INC. (JP) 2012-11-13 US claimed
US-8080564-B2 Hemodynamics improving agent AJINOMOTO CO., INC. (JP) 2011-12-20 US claimed
US-7767236-B2 Plant seed extract composition and process for producing the same AJINOMOTO CO., INC. (JP) 2010-08-03 US claimed
US-20090156657-A1 ANTI-INFLAMMATORY COMPOSITION AJINOMOTO CO., INC. (JP) 2009-06-18 US claimed
US-20080171781-A1 HEMODYNAMICS IMPROVING AGENT AJINOMOTO CO., INC. (JP) 2008-07-17 US claimed
US-7357951-B2 Composition for preventing atherosclerosis AJINOMOTO CO., INC. (JP) 2008-04-15 US claimed
US-20060257540-A1 Plant seed extract composition and process for producing the same AJINOMOTO CO., INC. (JP) 2006-11-16 US claimed
US-7084322-B2 Method for biosynthesizing the serotonin derivatives in plants CHONNAM NATIONAL UNIVERSITY (KR) 2006-08-01 US claimed
EP-1679079-A1 PLANT SEED EXTRACT COMPOSITION AND PROCESS FOR PRODUCING THE SAME Ajinomoto Co., Inc. (JP) 2006-07-12 EP claimed
US-20040268437-A1 Method for biosynthesizing the serotonin derivatives in plants CHONNAM NATIONAL UNIVERSITY (KR) 2004-12-30 US claimed
WO-2004113545-A1 METHOD FOR BIOSYNTHESIZING THE SEROTONIN DERIVATIVES IN PLANTS CHONNAM NATIONAL UNIVERSITY (KR) 2004-12-29 WO claimed
US-12507703-B2 Methods, devices and compositions for preserving human milk THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2025-12-30 US disclosed
EP-4654815-A1 UNSATURATED ALDEHYDES VIA RICE BIOTRANSFORMATION Symrise AG (DE) 2025-12-03 EP disclosed
US-20040268437-A1 Method for biosynthesizing the serotonin derivatives in plants CHONNAM NATIONAL UNIVERSITY (KR) 2004-12-30 US disclosed
WO-2004113545-A1 METHOD FOR BIOSYNTHESIZING THE SEROTONIN DERIVATIVES IN PLANTS CHONNAM NATIONAL UNIVERSITY (KR) 2004-12-29 WO disclosed
WO-2004113545-A1 METHOD FOR BIOSYNTHESIZING THE SEROTONIN DERIVATIVES IN PLANTS CHONNAM NATIONAL UNIVERSITY (KR) 2004-12-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12507703-B2 Methods, devices and compositions for preserving human milk LPL, CEL, LPO PTGS2 4537/4885ACHE 27/4885MAOB 293/4885
US-20090156657-A1 ANTI-INFLAMMATORY COMPOSITION VCAM1, ICAM1, TPH1 PTGS2 142/4885ACHE 990/4885MAOB 130/4885
US-20080171781-A1 HEMODYNAMICS IMPROVING AGENT TPH1, HTR1A, VASP PTGS2 85/4885ACHE 107/4885MAOB 66/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.