Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2240918 | 0.80 | CA12 (0.32) | BTKDGAT1GAA | |
| SCHEMBL6497827 | 0.75 | — | — | |
| SCHEMBL5997502 | 0.75 | EPHX1 (0.31) | EPHX1 | |
| SCHEMBL2064367 | 0.74 | HPGD (0.33) | DGAT1GAAEPHX1 | |
| SCHEMBL6608329 | 0.72 | HPGD (0.32) | DGAT1GAAEPHX1 | |
| SCHEMBL5568399 | 0.72 | HPGD (0.32) | DGAT1GAAEPHX1 | |
| SCHEMBL2877401 | 0.72 | DGAT1 (0.36) | DGAT1GAAEPHX1 | |
| SCHEMBL5421441 | 0.71 | HPGD (0.31) | DGAT1GAA | |
| SCHEMBL136090 | 0.71 | HPGD (0.31) | DGAT1GAA | |
| SCHEMBL1786719 | 0.70 | EPHX1 (0.30) | EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490367-B1 | IMIDAZOPYRIDINE DERIVATIVES AS KINASE INHIBITORS | GLAXO GROUP LTD (GB) | 2008-07-23 | — | — | EP | claimed |