SCHEMBL472019

SCHEMBL472019

CC1(C(=O)OC(F)C(F)F)CC2C=CC1C2

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 1/20 0.35
CETP P11597 1/20 0.32
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5184481 0.83 P2RX7 (0.37) P2RX7CETPCYP2D6CYP2C19
SCHEMBL3367328 0.83 P2RX7 (0.37) P2RX7CETPCYP2D6CYP2C19
SCHEMBL5347786 0.79 P2RX7 (0.35) P2RX7CETPCYP2D6CYP2C19
SCHEMBL1451757 0.78 CYP2D6 (0.36) P2RX7CETPCYP2D6CYP2C19
SCHEMBL5186802 0.78 CYP2D6 (0.36) P2RX7CETPCYP2D6CYP2C19
SCHEMBL200115 0.78 P2RX7 (0.41) P2RX7CETPCYP2D6CYP2C19
SCHEMBL18938394 0.78 P2RX7 (0.41) P2RX7CETPCYP2D6CYP2C19
SCHEMBL21593888 0.77 PRKCA (0.40) P2RX7CETPCYP2D6CYP2C19
SCHEMBL3364369 0.76 CYP2D6 (0.35) P2RX7CETPCYP2D6CYP2C19
SCHEMBL203304 0.76 P2RX7 (0.36) P2RX7CETPCYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2412732-B1 Method for preparing cyclic olefin addition polymer of high gas permeability SHINETSU CHEMICAL CO (JP) 2015-08-26 EP disclosed
US-8999043-B2 Air conditioning system DENSO CORPORATION (JP) 2015-04-07 US disclosed
US-20140165838-A1 AIR CONDITIONING SYSTEM DENSO CORPORATION (JP) 2014-06-19 US disclosed
US-8158732-B2 Method for preparing cyclic olefin addition polymer of high gas permeability SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-04-17 US disclosed
US-20120029158-A1 METHOD FOR PREPARING CYCLIC OLEFIN ADDITION POLYMER OF HIGH GAS PERMEABILITY SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-02-02 US disclosed
EP-2412732-A1 Method for preparing cyclic olefin addition polymer of high gas permeability Shin-Etsu Chemical Co., Ltd. (JP) 2012-02-01 EP disclosed
EP-2213691-A1 Cycloolefin addition polymer and making method Shin-Etsu Chemical Co., Ltd. (JP) 2010-08-04 EP disclosed
US-20100190950-A1 CYCLOOLEFIN ADDITION POLYMER AND MAKING METHOD SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-07-29 US disclosed
US-7049220-B2 Method of forming cavity between multilayered wirings JSR CORPORATION (JP) 2006-05-23 US disclosed
US-7015293-B2 Cycloolefin addition copolymer and optical transparent material JSR CORPORATION (JP) 2006-03-21 US disclosed
US-20050171310-A1 Cycloolefin addition copolymer and optical transparent material JSR CORPORATION (JP) 2005-08-04 US disclosed
EP-1538169-A1 CYCLOOLEFIN ADDITION COPOLYMER AND OPTICAL TRANSPARENT MATERIAL JSR Corporation (JP) 2005-06-08 EP disclosed
US-20040132243-A1 Method of forming cavity between multilayered wirings JSR CORPORATION (JP) 2004-07-08 US disclosed
EP-1416528-A2 Method of forming cavity between multilayered wirings JSR Corporation (JP) 2004-05-06 EP disclosed