Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7286509 | 0.94 | KDM4E (0.47) | KDM4ESLC6A9SLC6A5ALDH1A1MEN1 | |
| SCHEMBL1286420 | 0.93 | SLC6A9 (0.46) | KDM4ESLC6A9SLC6A5ALDH1A1MEN1 | |
| SCHEMBL11083674 | 0.81 | KMT2A (0.48) | KDM4ESLC6A9SLC6A5ALDH1A1KMT2A | |
| SCHEMBL11077996 | 0.78 | SLC6A9 (0.45) | MAPTSLC6A9SLC6A5 | |
| SCHEMBL4560310 | 0.72 | SLC6A4 (0.62) | — | |
| SCHEMBL7011050 | 0.72 | AGER (0.58) | SLC6A9SLC6A5ALDH1A1MEN1KMT2A | |
| SCHEMBL7287660 | 0.72 | SLC6A9 (0.40) | KDM4EMAPTSLC6A9SLC6A5ALDH1A1 | |
| SCHEMBL29111859 | 0.71 | KDM4E (0.82) | KDM4EMAPTGAAALDH1A1HSD17B10 | |
| SCHEMBL7287247 | 0.71 | SLC6A9 (0.49) | MAPTSLC6A9SLC6A5ALDH1A1MEN1 | |
| SCHEMBL15807707 | 0.70 | SLC6A2 (0.51) | KDM4EMAPTMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3116538-A1 | RESPIRATORY SYNCYTIAL VIRUS (RSV) REPLICATION INHIBITORS | Fondation The Ark (CH) | 2017-01-18 | — | — | EP | disclosed |
| WO-2017004672-A1 | PEPTIDYL TPOR ANTAGONISTS AND USES THEREOF | POLYMERS CRC LIMITED (AU) | 2017-01-12 | — | — | WO | disclosed |
| WO-2015135925-A1 | RESPIRATORY SYNCYTIAL VIRUS (RSV) REPLICATION INHIBITORS | FONDATION THE ARK (CH) | 2015-09-17 | — | — | WO | disclosed |
| EP-2412719-A1 | Chi-conotoxin peptides | Xenome Ltd (AU) | 2012-02-01 | — | — | EP | disclosed |
| EP-2386566-A2 | Chi-conotoxin peptides (II) | Xenome Ltd (AU) | 2011-11-16 | — | — | EP | disclosed |
| US-20110195909-A1 | NOVEL X-CONOTOXIN PEPTIDES (-II) | XENOME LTD. (AU) | 2011-08-11 | — | — | US | disclosed |
| EP-2015766-A1 | CYCLISED ALPHA-CONOTOXIN PEPTIDES | THE UNIVERSITY OF QUEENSLAND (AU) | 2009-01-21 | — | — | EP | disclosed |
| EP-1578787-A4 | NOVEL CHI-CONOTOXIN PEPTIDES (-II) | XENOME LTD (AU) | 2008-09-24 | — | — | EP | disclosed |
| WO-2007118270-A1 | CYCLISED ALPHA-CONOTOXIN PEPTIDES | THE UNIVERSITY OF QUEENSLAND (AU) | 2007-10-25 | — | — | WO | disclosed |
| EP-1578787-A1 | NOVEL CHI-CONOTOXIN PEPTIDES (-II) | Xenome Ltd (AU) | 2005-09-28 | — | — | EP | disclosed |
| WO-2004099238-A1 | NOVEL mu-CONOTOXIN PEPTIDES | THE UNIVERSITY OF QUEENSLAND (AU) | 2004-11-18 | — | — | WO | disclosed |
| WO-2004050688-A1 | NOVEL χ-CONOTOXIN PEPTIDES (-II) | XENOME LTD (AU) | 2004-06-17 | — | — | WO | disclosed |