Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | AGER | Q15109 | 3/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1286420 | 0.99 | SLC6A9 (0.46) | KDM4ESLC6A9SLC6A5MEN1KMT2A | |
| SCHEMBL472024 | 0.94 | KDM4E (0.49) | KDM4ESLC6A9SLC6A5MEN1KMT2A | |
| SCHEMBL11083674 | 0.87 | KMT2A (0.48) | KDM4ESLC6A9SLC6A5KMT2AAGER | |
| SCHEMBL11077996 | 0.84 | SLC6A9 (0.45) | SLC6A9SLC6A5AGER | |
| SCHEMBL7011050 | 0.79 | AGER (0.58) | SLC6A9SLC6A5MEN1KMT2AAGER | |
| SCHEMBL15807707 | 0.77 | SLC6A2 (0.51) | KDM4EMEN1KMT2AHTTNPSR1 | |
| SCHEMBL7287247 | 0.77 | SLC6A9 (0.49) | SLC6A9SLC6A5MEN1KMT2AAGER | |
| SCHEMBL11083984 | 0.76 | SLC6A9 (0.48) | SLC6A9SLC6A5MEN1KMT2AAGER | |
| SCHEMBL7290560 | 0.76 | MEN1 (0.44) | SLC6A9SLC6A5MEN1KMT2AALDH1A1 | |
| SCHEMBL11074785 | 0.75 | ALDH1A1 (0.38) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4440941-A | Aroyl-aminoacids, amides and esters thereof | USV PHARMACEUTICAL CORPORATION (US) | 1984-04-03 | — | — | US | disclosed |
| EP-0054936-A1 | Aroyl amino acids | USV PHARMACEUTICAL CORPORATION (US) | 1982-06-30 | — | — | EP | disclosed |