Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 6/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL291409 | 0.88 | HPGD (0.45) | BCAT2BLMCHEK1LMNAMAPT | |
| SCHEMBL4717730 | 0.82 | MAPT (0.48) | BCAT2BLMLMNAMAPTKMT2A | |
| SCHEMBL4720475 | 0.79 | BCAT2 (0.42) | BCAT2BLMCHEK1LMNAMAPT | |
| SCHEMBL4722651 | 0.78 | PDE4A (0.42) | BCAT2BLMLMNAMAPTKMT2A | |
| SCHEMBL4542766 | 0.77 | NOTUM (0.41) | BCAT2BLMLMNAMAPTKMT2A | |
| SCHEMBL4722672 | 0.76 | BCAT2 (0.43) | BCAT2BLMLMNAMAPTKMT2A | |
| SCHEMBL4721414 | 0.76 | MAPT (0.46) | BCAT2BLMLMNAMAPTKMT2A | |
| SCHEMBL5462039 | 0.73 | MAPT (0.49) | LMNAMAPTKMT2AHTTHPGD | |
| SCHEMBL290869 | 0.71 | HPGD (0.48) | BCAT2BLMLMNAMAPTKMT2A | |
| SCHEMBL8801360 | 0.68 | EGFR (0.57) | LMNAMAPTKMT2AHTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458722-B1 | PYRROLOPYRIMIDINES AS PHOSPHODIESTERASE VII INHIBITORS | MERCK PATENT GMBH (DE) | 2008-10-15 | — | — | EP | claimed |