Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | WDR5 | P61964 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 6/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4766122 | 0.85 | POLB (0.37) | POLBAPEX1CASP6CTDSP1TDP1 | |
| SCHEMBL4719504 | 0.73 | MEN1 (0.34) | POLBAPEX1CASP6CTDSP1TDP1 | |
| SCHEMBL6140578 | 0.66 | POLB (0.64) | POLBAPEX1CASP6CTDSP1TDP1 | |
| SCHEMBL10127582 | 0.66 | SIRT6 (0.56) | POLBALDH1A1KMT2ASLC6A9WDR5 | |
| SCHEMBL30619342 | 0.65 | PDE7A (0.47) | POLBTDP1ALDH1A1CYP3A4PDE7A | |
| SCHEMBL15123102 | 0.65 | PDE7A (0.47) | POLBTDP1ALDH1A1CYP3A4PDE7A | |
| SCHEMBL14101964 | 0.65 | — | — | |
| SCHEMBL31284605 | 0.64 | ABCC8 (0.41) | POLBCASP6ALDH1A1KMT2ASLC6A9 | |
| SCHEMBL30619305 | 0.63 | SLC6A9 (0.61) | ALDH1A1SLC6A9CYP1A2CYP2C9LMNA | |
| SCHEMBL28401990 | 0.63 | SLC6A9 (0.61) | ALDH1A1SLC6A9CYP1A2CYP2C9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |