Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 2/20 | 0.32 |
| ▸ | WDR5 | P61964 | 2/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.31 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.31 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.31 |
| ▸ | PHGDH | O43175 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4720477 | 1.00 | P2RX7 (0.37) | P2RX7MYCWDR5PDE3BPDE3A | |
| SCHEMBL4723793 | 0.91 | F10 (0.36) | P2RX7F10CXCR3PDE7A | |
| SCHEMBL4723789 | 0.91 | F10 (0.36) | P2RX7F10CXCR3PDE7A | |
| SCHEMBL4721019 | 0.90 | SMPD3 (0.37) | — | |
| SCHEMBL4721024 | 0.90 | SMPD3 (0.37) | — | |
| SCHEMBL4724015 | 0.90 | MAPT (0.34) | P2RX7NOTUM | |
| SCHEMBL4720017 | 0.89 | CXCR3 (0.31) | CXCR3 | |
| SCHEMBL4722249 | 0.89 | P2RX7 (0.38) | P2RX7MYCWDR5PDE3BPDE3A | |
| SCHEMBL4722245 | 0.89 | P2RX7 (0.38) | P2RX7MYCWDR5PDE3BPDE3A | |
| SCHEMBL4719363 | 0.88 | P2RX7 (0.36) | P2RX7F10RORCCXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |