Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.36 |
| ▸ | MYC | P01106 | 2/20 | 0.36 |
| ▸ | WDR5 | P61964 | 2/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4720711 | 1.00 | P2RX7 (0.42) | P2RX7RORCHSD11B1SOS1MYC | |
| SCHEMBL4722448 | 0.92 | RORC (0.41) | P2RX7RORCHSD11B1MYCWDR5 | |
| SCHEMBL4721709 | 0.92 | P2RX7 (0.39) | P2RX7RORCHSD11B1SOS1PDE3B | |
| SCHEMBL4721711 | 0.92 | P2RX7 (0.39) | P2RX7RORCHSD11B1SOS1PDE3B | |
| SCHEMBL4722454 | 0.92 | RORC (0.41) | P2RX7RORCHSD11B1MYCWDR5 | |
| SCHEMBL4724116 | 0.91 | P2RX7 (0.39) | P2RX7RORCHSD11B1SOS1PDE3B | |
| SCHEMBL4724121 | 0.91 | P2RX7 (0.39) | P2RX7RORCHSD11B1SOS1PDE3B | |
| SCHEMBL4723309 | 0.91 | P2RX7 (0.42) | P2RX7RORC | |
| SCHEMBL4723314 | 0.91 | P2RX7 (0.42) | P2RX7RORC | |
| SCHEMBL4723507 | 0.90 | ITGB2 (0.40) | P2RX7HSD11B1PDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |