Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14102077 | 0.91 | GPR119 (0.35) | GPR119PTK2 | |
| SCHEMBL4719000 | 0.84 | PTK2 (0.36) | PTK2GAA | |
| SCHEMBL14102074 | 0.79 | BRD9 (0.34) | GPR119PTK2 | |
| SCHEMBL4723056 | 0.76 | LMNA (0.32) | PTK2 | |
| SCHEMBL4722197 | 0.75 | MEN1 (0.32) | GAA | |
| SCHEMBL4720065 | 0.74 | POLB (0.31) | — | |
| SCHEMBL4720181 | 0.74 | NTRK1 (0.32) | — | |
| SCHEMBL4722031 | 0.73 | PTK2 (0.33) | PTK2 | |
| SCHEMBL4721894 | 0.73 | PTK2 (0.30) | PTK2 | |
| SCHEMBL4721092 | 0.73 | WNT3A (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |