Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 6/20 | 0.39 |
| ▸ | ACACB | O00763 | 3/20 | 0.35 |
| ▸ | LIPC | P11150 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.31 |
| ▸ | F10 | P00742 | 2/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4722867 | 0.94 | LIPG (0.37) | LIPGACACBLIPCFFAR1TTR | |
| SCHEMBL4722861 | 0.94 | LIPG (0.37) | LIPGACACBLIPCFFAR1TTR | |
| SCHEMBL4766330 | 0.88 | P2RX7 (0.36) | ACACBNOTUMF10F2 | |
| SCHEMBL4718837 | 0.88 | LIPG (0.39) | LIPGACACBLIPCFFAR1NOTUM | |
| SCHEMBL4720788 | 0.85 | LIPG (0.37) | LIPGACACBLIPCTTRNOTUM | |
| SCHEMBL4721540 | 0.85 | LIPG (0.37) | LIPGACACBLIPCTTRNOTUM | |
| SCHEMBL4720793 | 0.85 | LIPG (0.37) | LIPGACACBLIPCTTRNOTUM | |
| SCHEMBL4721956 | 0.84 | ACACB (0.34) | ACACBFFAR1F10F2 | |
| SCHEMBL4721962 | 0.84 | ACACB (0.34) | ACACBFFAR1F10F2 | |
| SCHEMBL4721893 | 0.84 | LIPG (0.35) | LIPGACACBLIPCFFAR1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |