SCHEMBL4721373

SCHEMBL4721373

Cc1ncccc1Oc1cc(OC2CCN(OC(=O)OC(C)C)CC2)ncn1

nearest known ligand 0.57

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 20/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4718741 0.87 GPR119 (0.49) GPR119
SCHEMBL4263519 0.87 GPR119 (0.75) GPR119
SCHEMBL4719808 0.85 GPR119 (0.49) GPR119
SCHEMBL4722977 0.84 GPR119 (0.55) GPR119
SCHEMBL4721322 0.83 GPR119 (0.58) GPR119
SCHEMBL4719031 0.80 GPR119 (0.59) GPR119
SCHEMBL4718453 0.80 GPR119 (0.79) GPR119
SCHEMBL4721341 0.79 GPR119 (0.43) GPR119
SCHEMBL4256496 0.77 GPR119 (0.56) GPR119
SCHEMBL4718680 0.76 GPR119 (0.55) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1756084-B1 SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES AS MODULATORS OF METABOLISM AND THE PROPHYLAXIS AND TREATMENT OF DISORDERS RELATED THERETO ARENA PHARM INC (US) 2008-11-26 EP claimed