Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14101707 | 0.88 | PARP1 (0.33) | MEN1CYP1A2CRHBPCASP1CYP2C19 | |
| SCHEMBL4719523 | 0.88 | P2RX7 (0.34) | MEN1CYP1A2CRHBPCASP1CYP2C19 | |
| SCHEMBL4721052 | 0.87 | MEN1 (0.31) | MEN1CYP1A2CRHBPCASP1CYP2C19 | |
| SCHEMBL4719078 | 0.86 | PARP1 (0.30) | MEN1CYP1A2CRHBPCASP1CYP2C19 | |
| SCHEMBL4719487 | 0.86 | — | — | |
| SCHEMBL4723349 | 0.85 | PTK2 (0.30) | — | |
| SCHEMBL4720122 | 0.83 | P2RX7 (0.34) | P2RX7 | |
| SCHEMBL4719220 | 0.83 | P2RX7 (0.34) | P2RX7 | |
| SCHEMBL4719218 | 0.83 | P2RX7 (0.34) | P2RX7 | |
| SCHEMBL4720247 | 0.82 | BACE1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |