Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.32 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.32 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4722804 | 0.92 | — | — | |
| SCHEMBL4719523 | 0.92 | P2RX7 (0.34) | — | |
| SCHEMBL4722854 | 0.85 | NOTUM (0.32) | BACE1BACE2 | |
| SCHEMBL4719705 | 0.84 | BACE1 (0.33) | BACE1BACE2IMPDH2LMNAPKM | |
| SCHEMBL4721704 | 0.82 | MEN1 (0.34) | — | |
| SCHEMBL4719487 | 0.82 | — | — | |
| SCHEMBL4719544 | 0.82 | CNR1 (0.33) | BACE1BACE2 | |
| SCHEMBL4722202 | 0.81 | CREBBP (0.36) | BACE1BACE2IMPDH2LMNAP2RY1 | |
| SCHEMBL4721258 | 0.81 | BACE1 (0.30) | BACE1BACE2 | |
| SCHEMBL4765691 | 0.80 | CREBBP (0.32) | BACE1BACE2IMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |